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Studying the Brain

From Structure to Function

How can researchers understand something as complex as the brain? By studying it at different biological scales—from individual cells and molecules to electrical activity and tissue organization. 


brown brain decor in selective-focus photography

Scientific pathway

1

SEE  - Microscopy

Visualize neural cells and tissue organization..

2

DENTIFY -Cellular Markers

Locate proteins and distinguish cellular populations.


3

MEASURE -Neural Activity

Record electrical signals produced by neurons.

4

ANALYZE -Molecular & Single-Cell Analysis

Examine genes, RNA and proteins to characterize neural cells at molecular resolution..

What does this Method  Reveal 

Research approachWhat researchers can investigate
MicroscopyStructure and spatial organization
ImmunofluorescenceProtein location and cellular markers
ElectrophysiologyElectrical activity and neuronal signaling
Molecular biologyGenes, RNA and proteins
Single-cell analysisCellular diversity and gene expression

Explore the Science

Go beyond the research pathway and explore external scientific resources covering the methods used to study neural cells and the nervous system.

microscopy

Microscopy 

Learn how microscopy is used to visualize cells, tissues and biological structures.

Nature Methods — Microscopy 

immunohistochemistry

Immunohistochemistry 

Explore antibody-based approaches used to identify proteins and cellular markers within tissues.

NCBI Bookshelf — Immunohistochemistry 

single-cell

Single-Cell Analysis

Discover technologies used to investigate individual cells and their molecular profiles. 

Nature Methods — Single-Cell Analysis

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